RT Journal Article T1 Correlation between Empirical Antibiotic Therapy and Bone Culture Results in Patients with Osteomyelitis A1 Tardaguila García, Aroa A1 Lázaro Martínez, José Luis A1 Sanz Corbalán, Irene A1 García Álvarez, Yolanda A1 Álvaro Afonso, Francisco Javier A1 García Morales, Esther Alicia AB Objective: To analyze the correlation between empirical antibiotic therapies prescribed in primary care centers by general practitioners and the microbiology results of bone culture in patients with diabetic foot-related osteomyelitis.Methods: This observational study involved 80 patients with diabetic foot ulcers and clinically suspected osteomyelitis. The patients were taking antibiotics prescribed by general practitioners to treat diabetic foot infections. Bone samples were taken from every patient for microbiology analysis in a specialized diabetic foot unit.Main outcome measure: The sensitivity of the bone cultures to antibiotics was compared with the patient's previous antibiotic therapy, and antibiotic and bacterial resistance were analyzed.Main results: The bone cultures from only 16 patients (22.3%) showed sensitivity to the antibiotics that the patient had been prescribed. Fifty-six patients (77.8%) displayed bacterial resistance to the antibiotic that they were taking.Conclusions: Awareness and implementation of international antibiotic stewardship guidelines are poor in primary care centers. It is important to establish strategies that foster a better understanding of treatment management standards and ensure the proper implementation of guidelines. PB Lippincott Williams & Wilkins SN 1538-8654 SN 1527-7941 YR 2019 FD 2019-01 LK https://hdl.handle.net/20.500.14352/96803 UL https://hdl.handle.net/20.500.14352/96803 LA eng NO Tardáguila-García A, Lázaro-Martínez JL, Sanz-Corbalán I, García-Álvarez Y, Álvaro-Afonso FJ, García-Morales E. Correlation between Empirical Antibiotic Therapy and Bone Culture Results in Patients with Osteomyelitis. Adv Skin Wound Care. 2019 Jan;32(1):41-44. doi: 10.1097/01.ASW.0000542527.48815.1f. PMID: 30376455. DS Docta Complutense RD 6 oct 2024