RT Journal Article
T1 Morphogenetic transitions in the adaptation of Candida albicans to the mammalian gut
A1 Alonso Monge, Rebeca María Del Mar
A1 Cortés Prieto, Isabel
A1 Román González, Elvira
A1 Pla Alonso, Jesús
AB Candida albicans is a pathobiont in humans that forms part of the mycobiota in healthy individuals and can cause different pathologies upon alterations of the host defenses. The mammalian gut is clinically relevant as this niche is the most common pool for bloodstream-derived infections. The ability of C. albicans to switch from yeast to hypha has been related to the commensal-to-pathogen transition and is, therefore, considered relevant in virulence. Recently, filaments have been implicated in the humoral response in the gut. C. albicans exhibits other morphologies that play different roles in pathogenicity and commensalism. This review focuses on the role of these morphological transitions in C. albicans proliferation and its establishment as a commensal in the mammalian gut, paying special attention to the transcription factors involved in their regulation.
PB Elsevier
SN 1286-4579
YR 2023
FD 2023-11-15
LK https://hdl.handle.net/20.500.14352/108886
UL https://hdl.handle.net/20.500.14352/108886
LA eng
NO Rebeca Alonso-Monge, Isabel Cortés-Prieto, Elvira Román, Jesús Pla, Morphogenetic transitions in the adaptation of Candida albicans to the mammalian gut, Microbes and Infection, Volume 26, Issue 3, 2024, 105253, https://doi.org/10.1016/j.micinf.2023.105253.
NO 2023 Acuerdos transformativos CRUE
DS Docta Complutense
RD 5 abr 2025