RT Journal Article T1 Breast reconstruction techniques with perforator flaps vs other surgical techniques in breast cancer A1 Martín Merino Acera, María del Rosario A1 Colmenarejo García, Esther A1 Ferrero San Román, Carla A1 Valdazo Gómez, Adela A1 Sánchez Egido, Iris A1 Latorre Marlasca, Lucía A1 Paseiro Crespo, Gloria Marta AB Introduction: Chest wall perforator flaps are increasingly used as volume replacement techniques in breast-conserving surgery for patients with unfavorable tumor-to-breast ratios or limited remodeling capacity. Their oncologic safety and complication profile compared to other standard techniques remain under evaluation.Methods: We conducted a retrospective comparative observational study of 346 patients undergoing breast cancer surgery between 2020 and 2024. Patients were divided into 4 groups: chest wall perforator flap reconstruction (n = 36), lumpectomy without reshaping (n = 161), lumpectomy with oncoplastic mammoplasty (n = 69), and mastectomy with or without immediate reconstruction (n = 80). Surgical complications were classified using Clavien-Dindo. Re-excision rates, local recurrence, and patient satisfaction (BREAST-Q) were evaluated.Results: Chest wall perforator flap patients had a complication rate of 11.1%, comparable to lumpectomy (11.8%) and oncoplastic mammoplasty (11.6%), and lower than mastectomy with reconstruction (23.1%). The re-excision rate in chest wall perforator flap was 13.9%, compared with 19.3% in lumpectomy and 17.4% in oncoplastic cases. No local or distant recurrences were observed in chest wall perforator flap patients during a mean follow-up of 21.4 months. Patient satisfaction in the chest wall perforator flap group was high, with 86.1% reporting favorable cosmetic outcomes.Conclusions: Chest wall perforator flap reconstruction offers complication and re-excision rates comparable to other surgical techniques, with excellent short-term oncologic safety and high patient satisfaction. They are a valuable option for selected patients undergoing breast-conserving surgery, particularly when tumor size or location limits the use of standard approaches. PB Elsevier SN 0039-6060 YR 2025 FD 2025-07-08 LK https://hdl.handle.net/20.500.14352/124349 UL https://hdl.handle.net/20.500.14352/124349 LA eng NO Martín-Merino Acera MDR, Colmenarejo García E, Ferrero San Román C, Valdazo Gómez A, Sánchez Egido I, Latorre Marlasca L, Paseiro Crespo G. Breast reconstruction techniques with perforator flaps vs other surgical techniques in breast cancer. Surgery. 2025 Oct;186:109586. doi: 10.1016/j.surg.2025.109586. Epub 2025 Aug 6. PMID: 40774048. DS Docta Complutense RD 2 oct 2025