RT Journal Article
T1 Perinatal outcome after ultrasound prenatal diagnosis of persistent right umbilical vein
A1 Martinez, Raquel
A1 Gámez Alderete, Francisco De Asis
A1 Bravo Arribas, Coral
A1 Sánchez, Pilar
A1 Orizales, Carmen
A1 Ortiz Quintana, Luis
A1 León Luis, Juan Antonio
AB ObjectiveOur aim was to describe ultrasound findings and perinatal outcome after prenatal diagnosis of persistent right umbilical vein (PRUV).Study designWe performed a retrospective analysis of fetuses with an ultrasound-based prenatal diagnosis of PRUV on record at 2 tertiary centers in Madrid, Spain. We describe clinical, maternal, fetal and perinatal variables for all cases.ResultsA total of 20,426 fetuses were delivered between the study centers. We detected 22 cases (0.1%) of PRUV. The male-to-female ratio was 1:1. All cases were intrahepatic type and diagnosed during the second and third trimesters (median, 21 weeks; IQR, 20–29 weeks). Doppler ultrasound revealed normal flow in the ductus venosus in all cases. Nine fetuses (40.9%) had additional ultrasound anomalies but no chromosomal abnormalities. Cardiovascular malformations were the most frequently associated congenital anomalies (4/9), followed by neurological malformations (2/9). In 5 of the cases with no concomitant anomalies, the weight of the newborn was below the tenth percentile for gestational age. Gestational development was normal for the remaining newborns. Delivery was unremarkable, and post-natal evolution was favorable.ConclusionOur results point to a potential association between PRUV and other fetal malformations and a very low rate of chromosomal abnormalities. Prenatal diagnosis of PRUV should be followed by detailed anatomical evaluation and echocardiography in order to rule out other structural malformations. The indication for a fetal karyotype study must be made on an individual basis considering PRUV type and other ultrasound findings.
PB Elsevier
SN 0301-2115
YR 2013
FD 2013-05
LK https://hdl.handle.net/20.500.14352/101103
UL https://hdl.handle.net/20.500.14352/101103
LA eng
NO Martinez R, Gamez F, Bravo C, Sánchez P, Orizales C, Ortiz L, De Leon-Luis J. Perinatal outcome after ultrasound prenatal diagnosis of persistent right umbilical vein. Eur J Obstet Gynecol Reprod Biol. 2013 May;168(1):36-9.
DS Docta Complutense
RD 22 abr 2025