TY - JOUR AU - Jacob, Tali Fishman AU - Singh, Vijay AU - Dixit, Mudit AU - Ginsburg-Shmuel, Tamar AU - Fonseca Vázquez, Begoña AU - Pintor Just, Jesús Jerónimo AU - Youdim, Moussa B. H. AU - Major, Dan T. AU - Weinreb, Orly AU - Fischer, Bilha PY - 2018 DO - 10.1007/s11302-018-9614-7 SN - 1573-9538 UR - https://hdl.handle.net/20.500.14352/12993 T2 - Purinergic Signalling AB - Extracellular nucleotides can regulate the production/drainage of the aqueous humor via activation of P2 receptors, thus affecting the intraocular pressure (IOP). We evaluated 5-OMe-UDP(α-B), 1A, a potent P2Y6-receptor agonist, for reducing IOP and... LA - eng M2 - 271 PB - Springer Verlag KW - Human P2Y6 receptor KW - P2Y6 receptor agonist KW - Glaucoma KW - Intraocular pressure KW - 5-OMe-uridine-5′-α-borano-diphosphate TI - A promising drug candidate for the treatment of glaucoma based on a P2Y6-receptor agonist TY - journal article VL - 14 ER -