TY  - JOUR
AU  - Cortes-Canteli, Marta
AU  - Kruyer, Anna
AU  - Fernandez-Nueda, Irene
AU  - Marcos-Diaz, Ana
AU  - Ceron, Carlos
AU  - T. Richards, Allison
AU  - C. Jno-Charles, Odella
AU  - Rodríguez Ramírez De Arellano, Ignacio
AU  - Callejas, Sergio
AU  - Norris, Erin H.
AU  - Sanchez-Gonzalez, Javier
AU  - Ruiz-Cabello Osuna, Jesús
AU  - Ibanez, Borja
AU  - Strickland, Sidney
AU  - Fuster, Valentín
PY  - 2019
DO  - 10.1016/j.jacc.2019.07.081
SN  - 0735-1097
UR  - https://hdl.handle.net/20.500.14352/133432
T2  - Journal of the American College of Cardiology
AB  - AD is a multifactorial disorder with a chronic pro-thrombotic component. This study combined physiological and molecular techniques to demonstrate that long-term anticoagulation with dabigatran ameliorated AD pathogenesis in an AD transgenic mouse...
LA  - eng
M2  - 1910
PB  - Elsevier
KW  - Cognitive impairment
KW  - oral anticoagulation
KW  - thrombin
KW  - thrombosis
KW  - neuroinflammation
KW  - animal models of human disease
TI  - Long-Term Dabigatran Treatment Delays Alzheimer's Disease Pathogenesis in the TgCRND8 Mouse Model
TY  - journal article
VL  - 74
ER  -