RT Journal Article T1 Can Large Artificial Intelligence-Based Linguistic Models Help to Obtain Information About Burning Mouth Syndrome? A1 Benito López, Paula A1 Adamo, Daniela A1 Caponio, Vito Carlo Alberto A1 González Serrano, José A1 dos Santos Silva, Alan Roger A1 Albuquerque, Rui A1 López Jornet, María Pía A1 Brailo, Vlaho A1 Farag, Arwa A1 Diniz Freitas, Márcio A1 Norma, Noburo A1 Ni Riordain, Richeal A1 López-Pintor Muñoz, Rosa María A1 Hernández Vallejo, Gonzalo AB Objective: Burning Mouth Syndrome (BMS) is an idiopathic chronic orofacial pain disorder with diagnostic and therapeutic challenges. Inexperienced clinicians may desperately resort to online information. The objective of this study was to evaluate the usefulness, quality, and readability of responses generated by three artificial intelligence large language models (AI-LLMs)-ChatGPT-4, Gemini, and Microsoft Copilot-to frequent questions about BMS.Materials and methods: Nine clinically relevant open-ended questions were identified through search-trend analysis and expert review. Standardized prompts were submitted, and responses were independently rated by 12 international experts using a 4-point usefulness scale. Quality was evaluated using the QAMAI tool. Readability was measured using Flesch-Kincaid Grade Level and Reading Ease scores. Statistical analyses included Kruskal-Wallis and Bonferroni correction.Results: All AI-LLMs produced moderately useful responses, with no significant difference in global performance. Gemini achieved highest overall quality scores, particularly in relevance, completeness, and source provision. Copilot scored lower in usefulness and source provision. No significant differences were obtained among AI-LLMs. Average readability corresponded to 12th grade, with ChatGPT requiring the highest proficiency.Conclusions: AI-LLMs show potential for generating reliable information on BMS, though variability in quality, readability, and source citation remains concerning. Continuous optimization is essential to ensure their clinical integration. PB Wiley SN 1354-523X YR 2025 FD 2025-08-31 LK https://hdl.handle.net/20.500.14352/123809 UL https://hdl.handle.net/20.500.14352/123809 LA eng NO Benito López P, Adamo D, Caponio VCA, González-Serrano J, Dos Santos Silva AR, de Pedro Herráez M, Albuquerque R, López Jornet MP, Brailo V, Farag A, Diniz Freitas M, Noma N, Riordain RN, Hernández G, López-Pintor RM. Can Large Artificial Intelligence-Based Linguistic Models Help to Obtain Information About Burning Mouth Syndrome? Oral Dis. 2025 Aug 31. doi: 10.1111/odi.70078 DS Docta Complutense RD 19 mar 2026