TY - JOUR AU - Lázaro‑Gorines, Rodrigo AU - López Rodríguez, Juan Carlos AU - Benedé Pérez, Sara AU - González, Miguel AU - Mayorga, Cristobalina AU - Vogel, Lothar AU - Martínez Del Pozo, Álvaro AU - Lacadena García-Gallo, Francisco Javier AU - Villalba Díaz, María Teresa PY - 2020 DO - 10.1038/s41598-020-69166-w UR - https://hdl.handle.net/20.500.14352/93544 T2 - Scientific Reports AB - Immunotoxins appear as promising therapeutic molecules, alternative to allergen-specifcimmunotherapy. In this work, we achieved the development of a protein chimera able to promote specifc cell death on efector cells involved in the allergic reaction.... LA - eng M2 - 12255 PB - Nature Research KW - Allergens KW - Animals KW - Antigens KW - Dermatophagoides KW - Arthropod Proteins KW - Basophils KW - Cell Degranulation KW - Cell Line KW - Cells KW - Cultured KW - Cysteine Endopeptidases KW - Dermatophagoides pteronyssinus KW - Desensitization KW - Immunologic KW - Humans KW - Hypersensitivity KW - Immunoglobulin E KW - Immunotoxins KW - Recombinant Proteins TI - Der p 1‑based immunotoxin as potential tool for the treatment of dust mite respiratory allergy TY - journal article VL - 10 ER -