TY - JOUR AU - López, Virginia AU - Tejedor, Juan Ramón AU - Carella, Antonella AU - García, María G. AU - Santamarina-Ojeda, Pablo AU - Pérez, Raúl F. AU - Mangas, Cristina AU - Urdinguio, Rocío G. AU - Aranburu, Aitziber AU - de la Nava, Daniel AU - Corte-Torres, María D. AU - Astudillo, Aurora AU - Mollejo, Manuela AU - Meléndez, Bárbara AU - Fernández, Agustín F. AU - Fraga, Mario F. PY - 2021 DO - 10.3389/fcell.2021.671838 UR - https://hdl.handle.net/20.500.14352/109897 T2 - Frontiers in Cell and Developmental Biology AB - Glioblastoma multiforme (GBM) is the most common and aggressive type of brain tumor in adulthood. Epigenetic mechanisms are known to play a key role in GBM although the involvement of histone methyltransferase KMT5B and its mark H4K20me2 has remained... LA - eng M2 - 671838 PB - Frontiers Media KW - Epigenetics KW - Glioblastoma KW - Histone methyltransferase KW - Histone posttranslational modification KW - Tumor suppresso TI - Epigenetic Deregulation of the Histone Methyltransferase KMT5B Contributes to Malignant Transformation in Glioblastoma TY - journal article VL - 9 ER -