RT Journal Article
T1 Further Advances in Atrial Fibrillation Research: A Metabolomic Perspective
A1 Arbeloa Gómez, Laura
A1 Álvarez Vidal, Jaime
A1 Izquierdo García, José Luis
AB Atrial fibrillation involves an important type of heart arrhythmia caused by a lack of control in the electrical signals that arrive in the heart, produce an irregular auricular contraction, and induce blood clotting, which finally can lead to stroke. Atrial fibrillation presents some specific characteristics, but it has been treated and prevented using conventional methods similar to those applied to other cardiovascular diseases. However, due to the influence of this pathology on the mortality caused by cerebrovascular accidents, further studies on the molecular mechanism of atrial fibrillation are required. Our aim here is provide a compressive review of the use of metabolomics on this condition, from the study of the metabolic profile of plasma to the development of animal models. In summary, most of the reported studies highlighted alterations in the energetic pathways related to the development of the condition.
PB MPDI
SN 2076-3417
YR 2022
FD 2022-03-21
LK https://hdl.handle.net/20.500.14352/72084
UL https://hdl.handle.net/20.500.14352/72084
LA eng
NO Unión Europea. Horizonte 2020
NO Ministerio de Ciencia e Innovación (MICINN)
NO Comunidad de Madrid
DS Docta Complutense
RD 17 jul 2024