RT Journal Article
T1 Community-Acquired Pneumonia among Patients with COPD in Spain from 2016 to 2019. Cohort Study Assessing Sex Differences in the Incidence and Outcomes Using Hospital Discharge Data
A1 Miguel Díez, Javier De
A1 López Herranz, Marta
A1 Hernández Barrera, Valentín
A1 Miguel Yanes, José María De
A1 Pérez Farinós, José Napoleón
A1 Wärnberg, Julia
A1 Carabantes Alarcón, David
A1 Jiménez García, Rodrigo
A1 López De Andrés, Ana Isabel
AB Background: To describe and analyze the incidence and hospital outcomes of patients admitted with community-acquired pneumonia (CAP) according to Chronic Obstructive Pulmonary Disease (COPD) status and sex in Spanish hospitals from 2016 to 2019.Methods: We conducted a cohort study using national hospital discharge data of all patients ≥40 years with CAP.Results: A total of 500,833 patients (59.0% men) was identified. Incidence of CAP increased over time. Age-adjusted incidence was 4.42-times higher in COPD patients. In-hospital mortality (IHM) was lower in men and women with COPD than in those without COPD (14.41% vs. 10.70% in men; 11.12% vs. 8.58%. in women; p < 0.001). The risk of dying in hospital increased with age, presence of several comorbidities (excluding T2DM that was a protective factor), and need for mechanical ventilation (non-invasive and invasive) during admission, irrespective of sex. Over time, the IHM decreased significantly in men and women with COPD. Men with COPD were significantly more likely to die in hospital than were COPD women (OR 1.13; 95% CI 1.07–1.21).Conclusions: Incidence of CAP was higher among subjects with COPD, although the effect of COPD was higher in men than in women. By contrast, IHM was lower in COPD patients, but men with COPD were significantly more likely to die in hospital than were COPD women.
PB MPDI
SN 2077-0383
YR 2021
FD 2021-10-23
LK https://hdl.handle.net/20.500.14352/4800
UL https://hdl.handle.net/20.500.14352/4800
LA eng
NO De Miguel Diez, J., López Herranz, M., Hernández Barrera, V. et al. «Community-Acquired Pneumonia among Patients with COPD in Spain from 2016 to 2019. Cohort Study Assessing Sex Differences in the Incidence and Outcomes Using Hospital Discharge Data». Journal of Clinical Medicine, vol. 10, n.o 21, octubre de 2021, p. 4889. DOI.org (Crossref), https://doi.org/10.3390/jcm10214889.
DS Docta Complutense
RD 10 abr 2025