TY - JOUR AU - Oset Gasque, María Jesús AU - González Prieto, María Del Pilar AU - Pérez Peña, Javier AU - García Font, Nuria AU - Romero Martínez, Manuel Alejandro AU - Pino Sans, Javier Del AU - Ramos Alonso, Eva AU - Hadjipavlou-Litina, Dimitra AU - Soriano, Elena AU - Chioua, Mourad AU - Samadi, Abdelouahid AU - Raghuvanshi, Dushyant S. AU - Singh, Krishna N. AU - Marco Contelles, José Luis PY - 2014 DO - 10.1016/j.ejmech.2013.12.021 SN - 0223-5234 UR - https://hdl.handle.net/20.500.14352/34800 T2 - European Journal of Medicinal Chemistry AB - The pharmacological analysis of racemic chromenotacrines (CT) 1e7, bearing the 11-amino-12-aryl-8,9,10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ol ring skeleton, in a series of experiments targeted to explore their potential use for the treatment of... LA - eng M2 - 491 PB - Elsevier KW - 11-Amino-12-aryl-8,9,10,12-tetrahydro-7Hchromeno[2,3-b]quinolin-3-ols KW - Tacrine analogs KW - Toxicity KW - EeAChE KW - hBuChE KW - Kinetic analysis KW - Inhibition mechanism KW - Antioxidant KW - Neuroprotection KW - Molecular modeling KW - ADMET KW - Alzheimer’s disease TI - Toxicological and pharmacological evaluation, antioxidant, ADMET and molecular modeling of selected racemic chromenotacrines {11-amino-12-aryl-8,9,10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ols} for the potential prevention and treatment of Alzheimer’s disease TY - journal article VL - 74 ER -