RT Journal Article
T1 Development of Geometry-Controlled All-Orthogonal BODIPY Trimers for Photodynamic Therapy and Phototheragnosis
A1 Prieto Castañeda, Alejandro
A1 García Garrido, Fernando
A1 Díaz Norambuena, Carolina
A1 Escriche Navarro, Blanca
A1 García Fernández, Alba
A1 Bañuelos, Jorge
A1 Rebollar, Esther
A1 García Moreno, Inmaculada
A1 Martínez Máñez, Ramón
A1 Moya Cerero, Santiago De La
A1 Rodríguez Agarrabeitia, Antonia
A1 Ortiz García, María Josefa
AB We have established an easy synthetic protocol for selectively developing all-orthogonal BODIPY trimers with unprecedented geometries on the basis of selecting methyl oxidation versus electrophilic formylation of key dimeric precursors. Photophysical characterization together with biological assays unraveled the most suitable BODIPY−BODIPY geometrical arrangements within the trimer, forcing them to serve as molecular platforms for the development of new, advanced heavy-atom-free photosensitizers for photodynamic therapy and phototheragnosis.
PB ACS
SN 1523-7060
YR 2022
FD 2022-05-16
LK https://hdl.handle.net/20.500.14352/72062
UL https://hdl.handle.net/20.500.14352/72062
LA eng
NO Prieto Castañeda, A., García Garrido, F., Díaz Norambuena, C. et al. «Development of Geometry-Controlled All-Orthogonal BODIPY Trimers for Photodynamic Therapy and Phototheragnosis». Organic Letters, vol. 24, n.o 20, mayo de 2022, pp. 3636-41. DOI.org (Crossref), https://doi.org/10.1021/acs.orglett.2c01169.
NO CRUE-CSIC (Acuerdos Transformativos 2022)
NO Ministerio de Ciencia, Innovación y Universidades (España)
NO Instituto de Salud Carlos III
NO Gobierno Vasco
NO Generalitat Valenciana
DS Docta Complutense
RD 1 sept 2024