RT Generic
T1 Data: Biological Performance of Duplex PEO + CNT/PCL Coating on AZ31B Mg Alloy for Orthopedic and Dental Applications
A1 Daavari, Morteza
A1 Atapour, Masoud
A1 Mohedano Sánchez, Marta
A1 Matykina, Endzhe
A1 Arrabal Durán, Raúl
A1 Nesic, Dobrila
AB To regulate the degradation rate and improve the surface biocompatibility of the AZ31B magnesium alloy, three different coating systems were produced via plasma electrolytic oxidation (PEO): simple PEO, PEO incorporating multi-walled carbon nanotubes (PEO + CNT), and a duplex coating that included a polycaprolactone top layer (PEO + CNT/PCL). Surfaces were characterized by chemical content, roughness, topography, and wettability. Biological properties analysis included cell metabolism and adhesion. PEO ± CNT resulted in an augmented surface roughness compared with the base material (BM), while PCL deposition produced the smoothest surface. All surfaces had a contact angle below 90°. The exposure of gFib-TERT and bmMSC to culture media collected after 3 or 24 h did not affect their metabolism. A decrease in metabolic activity of 9% and 14% for bmMSC and of 14% and 29% for gFib-TERT was observed after 3 and 7 days, respectively. All cells died after 7 days of exposure to BM and after 15 days of exposure to coated surfaces. Saos-2 and gFib-TERT adhered poorly to BM, in contrast to bmMSC. All cells on PEO anchored into the pores with filopodia, exhibited tiny adhesion protrusions on PEO + CNT, and presented a web-like spreading with lamellipodia on PEO + CNT/PCL. The smooth and homogenous surface of the duplex PEO + CNT/PCL coating decreased magnesium corrosion and led to better biological functionality.
PB MDPI
YR 2023
FD 2023-09-16
LK https://hdl.handle.net/20.500.14352/120472
UL https://hdl.handle.net/20.500.14352/120472
LA eng
NO Data for paper entitled, “Biological performance of duplex PEO+CNT/PCL coating on AZ31 magnesium alloy for orthopedic and dental applications” including: - Processed Data: Cell metabolism on different surfaces. Bone marrow MSCs (a) and gFib-TERTs (b) metabolism expressed as an absorbance ratio measured at 570 nm and 630 nm- Processed Images: Schematic summary of the coating development procedures , SEM images, topographical images, water contact angle measurements, cell adhesion and spreading on different surfaces
NO Agencia Estatal de Investigación
NO Ministerio de Ciencia, Innovación y Universidades
NO Avicenna Center of Excellence (ACE)
NO FEDER, UE
NO Comunidad de Madrid
NO Isfahan Research Network
DS Docta Complutense
RD 25 jun 2025