%0 Journal Article %A Borrero Del Pino, Juan %A Brede, Dag A. %A Skaugen, Morten %A Diep, Dzung B. %A Herranz Sorribes, Carmen %A Nes, Ingolf F. %A Cintas Izarra, Luis Miguel %A Hernández Cruza, Pablo Elpidio %T Characterization of Garvicin ML, a Novel Circular Bacteriocin Produced by Lactococcus garvieae DCC43, Isolated from Mallard Ducks (Anas platyrhynchos) %D 2011 %@ 0099-2240 %@ 1098-5336 %U https://hdl.handle.net/20.500.14352/115200 %X Lactococcus garvieae DCC43 produces a bacteriocin, garvicin ML (GarML), with a molecular mass of 6,004.2 Da. Data from de novo amino acid sequencing by tandem mass spectrometry and nucleotide sequencing by reverse genetics suggested that the bacteriocin is synthesized as a 63-amino-acid precursor with a 3-amino-acid leader peptide that is removed by cleavage. Subsequently, a covalent linkage between the N and C termini forms the mature version of this novel 60-amino-acid circular bacteriocin. %~