RT null T1 The pharmacology and clinical efficacy of matricaria recutita L.: a systematic review of in vitro, in vivo studies and clinical trials A1 Sánchez Gómez-Serranillos, Marta A1 González Burgos, Elena María A1 Gómez-Serranillos Cuadrado, María Pilar AB This systematic review shows the effectiveness of Matricaria chamomilla for improving health. Original papers and case reports published during 2014–2018 in PubMed, Science Direct and Scopus were included. Most studies were in vitro, performed with extracts, in 2018, and originated from Iran. In vitro assays focused mainly on antimicrobial, antiparasitic and anti-oxidant activities. In vivo studies specially investigated organ and tissue protective activity of chamomile. Clinical trials have validated some of these in vitro and in vivo pharmacological activities (diabetes mellitus, hyper-tension and pain). Future preclinical and clinical investigations should be aimed at deeping into pure compounds responsible for activities. PB Taylor&Francis YR 2022 FD 2022 LK https://hdl.handle.net/20.500.14352/125613 UL https://hdl.handle.net/20.500.14352/125613 LA eng NO Sánchez M, González-Burgos E, Gómez-Serranillos MP. The pharmacology and clinical efficacy of matricaria recutita L.: a systematic review of in vitro, in vivo studies and clinical trials. Food Reviews International 2022;38:1668–702. https://doi.org/10.1080/87559129.2020.1834577. DS Docta Complutense RD 21 ene 2026