TY - JOUR AU - García Hernández Miriam AU - García Aguilar, Ana AU - Burillo Maldonado, Jesús AU - Gómez Oca, Raquel AU - Manca, María Antonietta AU - Novials, Ana AU - Alcarraz-Vizarrán, Gema AU - Guillén Viejo, Carlos AU - Benito De Las Heras, Manuel R. PY - 2018 DO - 10.1038/s41419-018-0533-x UR - https://hdl.handle.net/20.500.14352/115680 T2 - Cell Death & Disease AB - Human islet amyloid polypeptide (hIAPP), or amylin, has the tendency to aggregate into insoluble amyloid fibrils, a typical feature of islets from type 2 diabetes individuals. Thus, we investigated comparatively the impact of hIAPP on key pathways... LA - eng M2 - 481 PB - Nature Publishing Group UK KW - Autophagy KW - Mitophagy KW - Amylin KW - Resveratrol KW - Type 2 diabetes TI - Pancreatic β cells overexpressing hIAPP impaired mitophagy and unbalanced mitochondrial dynamics TY - journal article VL - 9 ER -