RT Journal Article
T1 Influence of age on IgE response in peanut-allergic children and adolescents from the Mediterranean area
A1 García-Blanca, A.
A1 Aranda, A.
A1 Blanca-Lopez, N.
A1 Pérez, D.
A1 Gómez, F.
A1 Mayorga, C.
A1 Torres, M.J.
A1 Díaz-Perales, A.
A1 Perkins, J.R.
A1 Villalba, Mayte
A1 Blanca, M.
A1 Canto, G.
AB Background: Peanut allergens are common responsible of food allergy. Analyses of sensitization patterns, relationships with other allergens, clinical symptoms and variation with age are needed. We studied sensitization to Ara h 2, Ara h 9 and Pru p 3 in a population of children/adolescents allergic to peanut, and the relation with peach and pollen. Methods: Patients allergic to peanut were classified into two groups: A) allergic to peanut, and B) allergic to peach and peanut. The IgE response was measured to Ara h 2, Ara h 9 and Pru p 3.Results: Of 456 subjects evaluated, 28% were allergic to peanut. From this group 69% were sensitized to pollen. Urticaria was the most frequent entity followed by anaphylaxis and OAS. Fifty-nine percent had Ara h 2 and/or Ara h 9 specific IgE. Over half reported symptoms with peanut alone (Group A); 46% to peanut and peach (Group B). We observed significant differences in sex, age, onset of symptoms and sensitization to Artemisia. IgE response to Ara h 2 was more frequent in Group A; Ara h 9 and Pru p 3 in Group B. We observed a decrease in sensitization to Ara h 2 and an increase to Ara h 9 and Pru p 3 with increasing age. Conclusion: Peanut allergy is frequent in subjects with allergy to plant-foods, with Ara h 2 and Ara h 9 being two important allergens. In younger patients Ara h 2 predominates over Ara h 9. The reverse was observed in older patients.
PB Wiley-Blacwell
SN 0905-6157(Print)  1399-3038 (on line)
YR 2015
FD 2015-09
LK https://hdl.handle.net/20.500.14352/24201
UL https://hdl.handle.net/20.500.14352/24201
LA eng
NO FIS-Thematic Networks and Cooperative Research Centres: RIRAAF
NO Junta de Andalucía
DS Docta Complutense
RD 9 abr 2025