RT Patent
T1 Compuestos derivados de acrilato de 3-alquilamino-1H-indolilo y su uso en el tratamiento de las enfermeadades neurodegenerativas
A1 León Martínez, Rafael
A1 Buendia Abaitua, Izaskun
A1 Navarro González De Mesa, Elisa
A1 Michalska Dziama, Patrycja
A1 Gameiro Ros, Isabel
A1 Egea Máiquez, Franisco Javier
A1 García Lopez, Manuela
A1 García García, Juan Antonio
AB The invent relates to the methods for producing derivates of 3-alkylamino-1H-indole acrylate(I) with transcription factor Nrf2-inducing activity, free radical scavenging activity and neuroprotective ability. The invention also relates to the use of derivatives according to the invention of treatment of diseases, the pathogenesis of which involves oxidative stress, or diseases involving the deregulationof the activity of phase II genes activated by the factor Nrf2, such as Alzheimer´s disease, Parkinson´s disease, Huntington´s disease, multiple sclerosis, ictus or amyotrophic lateral sclerosis.
YR 2016
FD 2016-04-21
LK https://hdl.handle.net/20.500.14352/100853
UL https://hdl.handle.net/20.500.14352/100853
LA spa
NO León Martínez R, Buendia Abaitua I, Navarro González De Mesa E, Michalska Dziama P, Gameiro Ros I, Egea Máiquez FJ, et al. Compuestos derivados de acrilato de 3-alquilamino-1H-indolilo y su uso en el tratamiento de las enfermeadades neurodegenerativas 2016.
DS Docta Complutense
RD 9 sept 2025