RT Journal Article T1 Health-related quality of life and resilience in peri- and postmenopausal women during Covid-19 confinement A1 Coronado Martín, Pluvio Jesús A1 Fasero, Maria A1 Otero, Borja A1 Sanchez, Sonia A1 Viuda, Esther de la A1 Ramirez Polo, Isabel A1 Llaneza, Placido A1 Mendoza, Nicolas A1 Baquedano, Laura AB Objective: To assess the impact of confinement due to the coronavirus (Covid-19) pandemic on health-related quality of life (HRQoL) and resilience in peri- and postmenopausal women.Material and methods: We used an online questionnaire which was sent between April 30th and May 13th, 2020 to women aged 40-70 years who were peri- or postmenopausal according to STRAW criteria. We used the 16-item Cervantes short-form scale (Cervantes-SF) to measure HRQoL, and the 14-item Wagnild and Young Resilience Scale (RS-14) to measure resilience. High scores on the Cervantes-SF indicate low HRQoL and high scores on the RS-14 indicate high levels of resilience. Covid-19 status, sociodemographic descriptors, and lifestyle variables were also evaluated.Results: We included 2430 peri- and postmenopausal women with valid questionnaires. All items of the Cervantes-SF were completed in 2151 cases, whilst the RS-14 was completed in 2413 cases. There was a negative correlation between scores on the Cervantes-SF and RS-14 scales (Rho -0.350; p < 0.0001). Multiple linear regression analysis revealed a statistically significant association between Cervantes-SF scores and living with others (β-coefficient -10.2; p < 0.001), use of antidepressants (β 9.3; p < 0.001), physical activity (β -8.6; p < 0.001) and sexual activity (β -2.7; p < 0.001). Resilience was associated with the use of antidepressants (β -5.9; p < 0.001), physical activity (β 3.2; p < 0.001) and sexual activity (β 1.7; p = 0.005). According to the multivariate analysis, there were no associations between either Covid-19 or menopausal status and HRQoL or resilience scores.Conclusions: During the period of mandatory Covid-19 confinement, peri- and postmenopausal women who engaged in physical and sexual activity had higher HRQoL and higher levels of resilience, whilst women who were using antidepressants had lower HRQoL and lower levels of resilience. HRQoL was greater in women who lived with others. PB Elsevier YR 2021 FD 2021-02-10 LK https://hdl.handle.net/20.500.14352/128840 UL https://hdl.handle.net/20.500.14352/128840 LA eng NO Coronado PJ, Fasero M, Otero B, Sanchez S, Viuda E, Ramirez-Polo I, Llaneza P, Mendoza N, Baquedano L. Health-related quality of life and resilience in peri- and postmenopausal women during Covid-19 confinement. Maturitas. 2021 Feb;144:4-10. doi: 10.1016/j.maturitas.2020.09.004. Epub 2020 Sep 28. PMID: 33358207; PMCID: PMC7521907. DS Docta Complutense RD 1 ene 2026