RT Journal Article T1 Endothelial damage with cataract surgery techniques A1 Díaz Valle, David A1 Benítez Del Castillo Sánchez, José Manuel A1 Castillo Gómez, Alfredo A1 Sayagues, Octavio A1 Moriche, Manuel AB Purpose: To evaluate intraoperative endothelial damage after planned extracapsular cataract extraction (ECCE) with different capsulotomy techniques and phacoemulsification.Settings: San Carlos University Hospital, Castroviejo Institute, Madrid, Spain.Methods: In this prospective, randomized study, 60 patients with senile cataract scheduled for cataract surgery were divided into three groups of 20 each: Group 1 had phacoemulsification; Group 2, planned ECCE with continuous curvilinear capsulorhexis; and Group 3, ECCE with letter-box capsulotomy. Preoperatively and 3 months postoperatively, endothelial cell density, percentage of hexagonality, and the cell size variation coefficient were determined by contact specular microscopy; endothelial permeability was examined by anterior segment fluorophotometry and central comeal thickness, by ultrasonic pachymetry. Results were analyzed using the two-tailed Students t-test and analysis of variance.Results: In all three groups, endothelial permeability and cell loss increased significantly from the preoperative values, but there were no significant differences among the postoperative values. Mean cell loss was 11.8% in Group 1, 12.8% in Group 2, and 10.1% in Group 3. There were no differences between the preoperative and postoperative morphometric indexes. Postoperative pachymetric measurements were not significant.Conclusions: Endothelial response was not statistically significantly different among the surgical techniques, although endothelial damage was lower in Group 3, which could indicate a protective effect of the anterior capsule during cataract extraction. Endothelial barrier function remained disturbed despite the apparent morphological stabilization. PB Elsevier SN 0886-3350 YR 1998 FD 1998-07-15 LK https://hdl.handle.net/20.500.14352/112594 UL https://hdl.handle.net/20.500.14352/112594 LA eng NO Díaz-Valle, David, et al. «Endothelial Damage with Cataract Surgery Techniques». Journal of Cataract and Refractive Surgery, vol. 24, n.o 7, julio de 1998, pp. 951-55. DOI.org (Crossref), https://doi.org/10.1016/S0886-3350(98)80049-7. DS Docta Complutense RD 17 abr 2025