RT Journal Article
T1 Human congenital T-cell receptor disorders
A1 Marín Marín, Ana Victoria
A1 Garcillán Goyoaga, Beatriz de
A1 Jiménez Reinoso, Anaïs
A1 Muñoz Ruiz, Miguel
A1 Briones Contreras, Alejandro
A1 Fernández Malavé, Edgar
A1 Recio Hoyas, María José
A1 Regueiro González-Barros, José Ramón
AB Immunodeficiencies of most T-cell receptor (TCR) components (TCRID) have been reported in almost 40 patients worldwide who have also, at times, shown signs of autoimmunity. We updated their clinical, immunological, and molecular features with an emphasis on practical diagnosis, as the range of the disorder grows in complexity with new partial defects. Cellular and animal models are also reviewed and in some cases reveal their limitations for predicting TCRID immunopathology.
PB Canadian Science Publishing
SN 2292-5937; 2292-5945
YR 2015
FD 2015
LK https://hdl.handle.net/20.500.14352/34395
UL https://hdl.handle.net/20.500.14352/34395
LA eng
NO Ministerio de Economia y Competitividad (MINECO)
NO Comunidad de Madrid
NO Insituto de Salud Carlos III (ISCIII)
NO Fundacion Lair
DS Docta Complutense
RD 20 jul 2024