RT Journal Article
T1 Enhanced production of therapeutic metabolites in cork-oak somatic embryos under abiotic stress conditions
A1 Pintos López, Beatriz
A1 Manzanera, José Antonio
A1 Pérez-Urría Carril, Elena
A1 Jiménez, Carlos
A1 Montoro, Alba
A1 Gomez Garay, Arancha
AB This study investigates the enhanced production of key therapeutic metabolites (ellagic acid, serotonin, and chlorogenic acid) in response to abiotic stress in in vitro cultures of Quercus suber somatic embryos. Findings indicate significant increases in metabolite levels under various stress conditions, highlighting the potential for commercial-scale production of these compounds, known for their antioxidant, anticancer, and anti-COVID-19 properties. Under osmotic/saline stress, ellagic acid production significantly increased, representing an 80% increase compared to control conditions. In embryos exposed to different stressors, serotonin accumulation showed a six-fold increase under osmotic/saline stress. Although the elicitors used did not increase chlorogenic acid levels, exploring alternative stress types may enhance its production. This research paves the way for sustainable, large-scale production of health-beneficial metabolites, addressing global health challenges and promoting resource sustainability.
PB MDPI
SN 2673-7140
YR 2024
FD 2024-09
LK https://hdl.handle.net/20.500.14352/112097
UL https://hdl.handle.net/20.500.14352/112097
LA eng
NO López, B.P.; Manzanera, J.A.; Pérez-Urria, E.; Jiménez, C.; Montoro, A.; Gomez-Garay, A. Enhanced Production of Therapeutic Metabolites in Cork-Oak Somatic Embryos under Abiotic Stress Conditions. Stresses 2024, 4, 546-557. https://doi.org/10.3390/stresses4030035
DS Docta Complutense
RD 12 abr 2025