RT Journal Article T1 Two-dimensional echocardiographic features of the inferior right atrial isthmus: The role of vestibular thickness in catheter ablation of atrial flutter A1 Marcos Alberca, Pedro A1 Sánchez Quintana, Damián A1 Cabrera, José A. A1 Farré, Jerónimo A1 Rubio, José M. A1 De Agustín Loeches, José Alberto A1 Almería, Carlos A1 Pérez De Isla, Leopoldo A1 Macaya Miguel, Carlos AB ObjectivesThe aim of this study was to examine the feasibility of transthoracic two-dimensional (2D)-echocardiography in defining the cavo-tricuspid isthmus (CTI) anatomy and its value concerning the ease of catheter ablation of isthmic atrial flutter (AF).MethodsCTI analysis was accomplished in 39 cases: 16 necropsy specimens and 23 patients. Sixteen were patients with isthmus-dependent AF and seven controls with other supraventricular re-entrant tachycardias. Two-dimensional transthoracic echocardiography and a right atrium angiogram were performed before radiofrequency catheter ablation (RFCA).ResultsThe measurements of the CTI with angiography were compared with those taken with echocardiography and correlation was excellent (r= 0.91; P < 0.0001). In normal patients, the dimension of the vestibular thickness was successfully compared and validated with the histological examination of the necropsy specimens: histology median 6.8 mm, range 4.4–10.5 vs. echo median 6.2 mm, range 5.4–8.7; P: NS. Vestibular thickness was greater in complex than in simple RFCA (13.6 ± 1.9 mm vs. 10.0 ± 2.3 mm; P = 0.01). When vestibular thickness ≥11.5 mm, the ablation prone to be complex (sensitivity 83.3%, specificity 80%, positive predictive value 71.4%, and negative predictive value 88.9%).ConclusionsTwo-dimensional transthoracic echocardiography clearly depicts the inferior isthmus and, displaying the thickness of the tricuspid vestibule, it was related with complexity of the ablation procedure in isthmus-dependent AF. PB Oxford Academic SN 2047-2404 YR 2013 FD 2013-06-09 LK https://hdl.handle.net/20.500.14352/131929 UL https://hdl.handle.net/20.500.14352/131929 LA eng NO Marcos-Alberca P, Sánchez-Quintana D, Cabrera JA, Farré J, Rubio JM, de Agustín JA, Almería C, Pérez-Isla L, Macaya C. Two-dimensional echocardiographic features of the inferior right atrial isthmus: the role of vestibular thickness in catheter ablation of atrial flutter. Eur Heart J Cardiovasc Imaging. 2014 Jan;15(1):32-40. doi: 10.1093/ehjci/jet112 DS Docta Complutense RD 30 mar 2026