RT Journal Article T1 Aclaramiento de creatinina y nefropatía por contraste en pacientes con creatinina normal A1 De Agustín Loeches, José Alberto A1 Carda, Rocío A1 Manzano, María del C. A1 Ruiz-Mateos, Borja A1 García-Rubira, Juan C. A1 Fernández Ortiz, Antonio Ignacio A1 Vilacosta, Isidre A1 Macaya Miguel, Carlos AB The main risk factor for contrast nephropathy is the presence of poor renal function. Plasma creatinine level is not a reliable measure of renal function as its value could lie within the normal range despite the presence of significant nephropathy. The purpose of this study was to evaluate the creatinine clearance rate as a predictor of contrast nephropathy in patients with a normal plasma creatinine level. The study included 273 consecutive patients with non-ST elevation acute coronary syndrome (NSTEACS) and a normal plasma creatinine level at admission who underwent coronary angiography. Patients who developed contrast nephropathy had a lower creatinine clearance rate at admission (66.3 mL/min vs. 83.4 mL/min; P<.001). A creatinine clearance rate < 80 mL/min had a sensitivity of 81% for predicting contrast nephropathy. Creatinine clearance should be measured routinely in patients with NSTEACS who are scheduled for coronary angiography. PB Elsevier SN 1579-2242 YR 2007 FD 2007 LK https://hdl.handle.net/20.500.14352/132000 UL https://hdl.handle.net/20.500.14352/132000 LA eng NO de Agustín, J. A., Carda, R., Manzano, M.delC., Ruiz-Mateos, B., García-Rubira, J. C., Fernández-Ortiz, A., Vilacosta, I., & Macaya, C. (2007). Aclaramiento de creatinina y nefropatía por contraste en pacientes con creatinina normal [Creatinine clearance and contrast nephropathy in patients with normal creatinine levels]. Revista espanola de cardiologia, 60(7), 772–776. DS Docta Complutense RD 20 mar 2026