TY - JOUR AU - Alcolea Alcolea, Pedro José AU - Larraga, Jaime AU - Rodríguez-Martín, Daniel AU - Alonso, Ana AU - Loayza, Francisco AU - Rojas, José M. AU - Ruiz García, Silvia AU - Louloudes Lázaro, Andrés AU - Carlón, Ana B. AU - Sánchez Cordón, Pedro José AU - Nogales Altozano, Pablo AU - Redondo, Natalia AU - Manzano García, Miguel AU - Lozano Borregón, Daniel AU - Palomero, Jesús AU - Montoya, María AU - Vallet Regí, María Dulce Nombre AU - Martín García, Verónica AU - Sevilla, Noemí AU - Larraga, Vicente PY - 2022 DO - 10.3389/fimmu.2022.1023255 SN - 1664-3224 UR - https://hdl.handle.net/20.500.14352/73418 T2 - Frontiers in Immunology AB - SARS-CoV-2 vaccines currently in use have contributed to controlling the COVID-19 pandemic. Notwithstanding, the high mutation rate, fundamentally in the spike glycoprotein (S), is causing the emergence of new variants. Solelyutilizing this antigen is... LA - eng PB - Frontiers Media KW - SARS-CoV-2 KW - DNA vaccine KW - S protein KW - N protein KW - Mouse model KW - pPAL KW - Furin TI - Non-replicative antibiotic resistance-free DNA vaccine encoding S and N proteins induces full protection in mice against SARS-CoV-2 TY - journal article VL - 13 ER -