TY - JOUR AU - Tomás-Cortázar, Julen AU - Martín-Ruiz, Itziar AU - Barriales, Diego AU - Pascual-Itoiz, Miguel Ángel AU - de Juan, Virginia Gutiérrez AU - Caro-Maldonado, Alfredo AU - Merino, Nekane AU - Marina, Alberto AU - Blanco, Francisco J. AU - Flores Landeira, Juana María AU - Sutherland, James D. AU - Barrio, Rosa AU - Rojas, Adriana AU - Martínez-Chantar, María Luz AU - Carracedo, Arkaitz AU - Simó, Carolina AU - García-Cañas, Virginia AU - Abecia, Leticia AU - Lavín, José Luis AU - Aransay, Ana M. AU - Rodríguez, Héctor AU - Anguita, Juan PY - 2017 DO - 10.1038/s41598-017-11354-2 UR - https://hdl.handle.net/20.500.14352/125909 T2 - Scientific Reports AB - Salp15, a salivary protein of Ixodes ticks, inhibits the activation of naïve CD4 T cells. Treatment with Salp15 results in the inhibition of early signaling events and the production of the autocrine growth factor, interleukin-2. The fate of the CD4 T... LA - eng M2 - 1 PB - Nature Research KW - Versus-Host-Disease KW - Regulatory T-Cells KW - Salivary Protein KW - Immunity KW - CD4 KW - Inflamation KW - Infection KW - Modulation KW - Neoplasms KW - Marker TI - The immunosuppressive effect of the tick protein, Salp15, is long-lasting and persists in a murine model of hematopoietic transplant TY - journal article VL - 7(1) ER -