TY - JOUR AU - Aleo Luján, Esther AU - Lopez Picado, Amanda AU - Rivas Paterna, Ana Belén AU - Joyanes Albacens, Belen AU - Rodríguez Rojo, Marina Laura AU - Fernández García, Patricia AU - Soto Beauregard, María Del Carmen AU - Rodriguez Alarcon, Jaime AU - Gonzalez Perrino, Carlos AU - San Pedro de Urquiza, Borja AU - Arias, Eva AU - Rodriguez, Diamelis AU - Esteban Polonio, Carmen AU - Torrejon, Maria José PY - 2020 DO - 10.1186/s13063-019-3906-2 UR - https://hdl.handle.net/20.500.14352/117477 T2 - Trials AB - BackgroundSurgery can generate significant stress and anxiety in up to 70% of the paediatric population. There are several pharmacological and non-pharmacological strategies to reduce pre-operative anxiety in children, however, they have several side... LA - eng M2 - 1 PB - BMC TI - Pre-operative anxiolysis in children through a combined pharmacological therapy with hydroxyzine and a non-pharmacological distraction technique with a clown (SONRISA): study protocol for randomised double-blind clinical trial TY - journal article VL - 21 ER -