RT Journal Article
T1 Multi-functional oxidase-like activity of praseodymia nanorods and nanoparticles
A1 Jiang, Lei
A1 Han, Yaning
A1 Fernández García, Susana
A1 Tinoco Rivas, Miguel
A1 Li, Zhuang
A1 Nan, Pengli
A1 Sun, Jingtao
A1 Delgado, Juan José
A1 Pan, Huiyan
A1 Blanco, GInesa
A1 Martínez López, Javier
A1 Hungría, Ana Belén
A1 Calvino, José Juan
A1 Chen, Xioawei
AB The ability to mimic protein-based oxidase with multi-functional inorganic nanozymes would greatly advance biomedical and clinical practices. Praseodymia (PrOx) nanorods (NRs) and nanoparticles (NPs) have been synthesized using hydrothermal and precipitation methods. Both PrOx catalysts with different morphologies exhibit significantly higher oxidase-like activities (Michaelis-Menten constant Km ≤ 0.026 mM) than commercial PrOx and most so-far-reported artificial enzymes. One of the substrates, dopamine, can be oxidized and further polymerized to generate polydopamine in acidic conditions. Akin to CeO2, which is a well-studied nanozyme, a different mechanism involving holes+, oxygen vacancies and oxygen mobility over PrOx catalysts has been proposed in this work. However, fluoride ions were found to impose opposite effects on the oxidase-mimicking activity of PrOx and CeO2, implying a promising path for the exploration of new nanozymes. In support of this, PrOx was further applied in colorimetric sensing of L-cysteine and fluoride with high sensitivity
PB Elsevier
YR 2023
FD 2023
LK https://hdl.handle.net/20.500.14352/93168
UL https://hdl.handle.net/20.500.14352/93168
LA eng
NO Ministerio de Ciencia, Innovación y Universidades (España)
NO Junta de Andalucía
NO Natural Science Foundation of Shandong Province (China)
DS Docta Complutense
RD 12 abr 2025