RT Journal Article
T1 Antifungal and Antiparasitic Drug Delivery
A1 Torrado Durán, Juan José
A1 Serrano López, Dolores Remedios
A1 Capilla, Javier
AB Fungal and parasitic diseases affect more than a billion people across the globe, one-sixth of the world’s population, mostly located in developing countries. The lack of effective and safer treatments combined with a deficient diagnosis lead to serious chronic illness or even death. There is a mismatch between the rate of drug resistance and the development of new medicines. Formulation of antifungal and antiparasitic drugs adapted to different administration routes is challenging, bearing in mind their poor water solubility, which limits their bioavailability and efficacy. Hence, there is an unmet clinical need to develop vaccines and novel formulations and drug delivery strategies that can improve the bioavailability and therapeutic effect by enhancing their dissolution, increasing their chemical potency, stabilising the drug and targeting high concentration of drug to the infection sites. This Editorial regards the ten research contributions presented in the Special Issue “Antifungal and Antiparasitic Drug Delivery”.
PB MDPI
SN 1999-4923
YR 2020
FD 2020-04-04
LK https://hdl.handle.net/20.500.14352/6777
UL https://hdl.handle.net/20.500.14352/6777
LA eng
DS Docta Complutense
RD 30 abr 2024