TY - JOUR AU - Hennessy, Edel AU - Gormley, Shane AU - López Rodríguez, Ana Belén AU - Murray, Caoimhe AU - Murray, Carol AU - Cunningham, Colm PY - 2017 DO - 10.1016/j.bbi.2016.09.011 SN - 0889-1591 UR - https://hdl.handle.net/20.500.14352/18036 T2 - Brain, Behavior, and Immunity AB - Inflammation influences chronic neurodegeneration but its precise roles are not yet clear. Systemic inflammation caused by infection, trauma or co-morbidity can alter the brain’s inflammatory status, produce acute cognitive impairments, such as... LA - eng M2 - 233 PB - Elsevier KW - TNF-α KW - Systemic inflammation KW - Microglia KW - Sickness KW - Behavior KW - Dementia KW - Delirium TI - Systemic TNF-α produces acute cognitive dysfunction and exaggerated sickness behavior when superimposed upon progressive neurodegeneration TY - journal article VL - 59 ER -