RT Journal Article
T1 Adult Mesenchymal Stem Cells from Oral Cavity and Surrounding Areas: Types and Biomedical Applications
A1 Cabaña Muñoz, María Eugenia
A1 Pelaz Fernández, María Jesús
A1 Parmigiani Cabaña, José María
A1 Parmigiani Izquierdo, José María
A1 Merino Martín, José Joaquín
AB Adult mesenchymal stem cells are those obtained from the conformation of dental structures (DMSC), such as deciduous and permanent teeth and other surrounding tissues. Background: The self-renewal and differentiation capacities of these adult stem cells allow for great clinical potential. Because DMSC are cells of ectomesenchymal origin, they reveal a high capacity for complete regeneration of dental pulp, periodontal tissue, and other biomedical applications; their differentiation into other types of cells promotes repair in muscle tissue, cardiac, pancreatic, nervous, bone, cartilage, skin, and corneal tissues, among others, with a high predictability of success. Therefore, stem and progenitor cells, with their exosomes of dental origin and surrounding areas in the oral cavity due to their plasticity, are considered a fundamental pillar in medicine and regenerative dentistry. Tissue engineering (MSCs, scaffolds, and bioactive molecules) sustains and induces its multipotent and immunomodulatory effects. It is of vital importance to guarantee the safety and efficacy of the procedures designed for patients, and for this purpose, more clinical trials are needed to increase the efficacy of several pathologies. Conclusion: From a bioethical and transcendental anthropological point of view, the human person as a unique being facilitates better clinical and personalized therapy, given the higher prevalence of dental and chronic systemic diseases.
PB MDPI
SN 1999-4923
YR 2023
FD 2023-08-09
LK https://hdl.handle.net/20.500.14352/111912
UL https://hdl.handle.net/20.500.14352/111912
LA eng
NO Cabaña-Muñoz, M.E.; Pelaz Fernández, M.J.; Parmigiani-Cabaña, J.M.; Parmigiani-Izquierdo, J.M.; Merino, J.J. Adult Mesenchymal Stem Cells from Oral Cavity and Surrounding Areas: Types and Biomedical Applications. Pharmaceutics 2023, 15, 2109. https://doi.org/10.3390/pharmaceutics15082109
NO 2023 Descuento MDPI
DS Docta Complutense
RD 17 abr 2025