TY - JOUR AU - Papkou, Andrei AU - García Pastor, Lucía AU - Escudero García-Calderón, José Antonio AU - Wagner, Andreas PY - 2023 DO - 10.1126/science.adh3860 SN - 0036-8075 UR - https://hdl.handle.net/20.500.14352/95057 T2 - Science AB - Fitness landscape theory predicts that rugged landscapes with multiple peaks impair Darwinian evolution, but experimental evidence is limited. In this study, we used genome editing to map the fitness of >260,000 genotypes of the key metabolic enzyme... LA - eng M2 - eadh3860 PB - American Association for the Advancement of Science TI - A rugged yet easily navigable fitness landscape TY - journal article VL - 382 ER -