RT Journal Article T1 Striated duct adenoma: The cytological description of a rare entity A1 De La Torre Serrano, Montserrat A1 Alarcón García, Lorenzo A1 Colino Gallardo, Ana María A1 Vega González, Jesús A1 Bergillos Giménez, María Reyes A1 Hernández Martínes, Desiré A1 García Egido, Alejandro A1 Iglesias Moreno, María Cruz A1 Pérez Alonso, Pablo A1 Plaza Hernández, José Carlos A1 Fernández Aceñero, María Jesús AB IntroductionStriated duct adenoma is a benign salivary gland tumour recently recognized by the World Health Organization. To date, no report has described the cytological features of this entity.Materials and MethodsWe report the case of a 60-year-old woman with a tumour in the right parotid gland with a diameter greater than 2.4 cm confirmed by imaging tests.ResultsTwo fine-needle aspiration cytologies (FNAC) were performed with inconclusive results, reporting epithelioid and spindle-shaped cellularity, with little stroma, and nuclei with abundant pseudoinclusions. Myoepithelioma and Schwannoma were proposed as differential diagnoses. An immunocytochemical panel was performed, showing positivity for S-100, SOX10, CK7 and vimentin, and negativity for both myoepithelial (p63 and calponin) and thyroid markers. In the absence of a conclusive diagnosis, the patient accepted surgery. The biopsy results confirmed diagnosis of striated duct adenoma, with immunohistochemical features superimposable to cytology.ConclusionLittle information is available in the literature, both on biopsy and, more strikingly, on cytology of this neoplasm. The aim of this work is to provide cytological characteristics that allow diagnosis of this entity with FNAC and thus avoid unnecessary surgeries. PB Wiley SN 0956-5507 YR 2024 FD 2024-08-21 LK https://hdl.handle.net/20.500.14352/119086 UL https://hdl.handle.net/20.500.14352/119086 LA eng NO De La Torre Serrano M, Alarcón García L, Colino Gallardo AM, et al. Striated duct adenoma: The cytological description of a rare entity. Cytopathology. 2025; 36: 56-62. doi:10.1111/cyt.13441 DS Docta Complutense RD 3 may 2025