RT Journal Article
T1 Aplastic anaemia treated using eltrombopag in a dog
A1 Rodríguez Cobos, Alfredo
A1 Atencia Fernández, Sabela María
AB A 2-year-old, neutered, female beagle was presented to a referral hospital for investigation of pancytopenia. The patient had a history of recurrent infections and, on previous blood tests, anaemia, leukopenia and thrombocytopenia were detected. At the time of presentation, the patient had been treated for 2 weeks with omeprazole, amoxicillin-clavulanic acid, marbofloxacin and gabapentin, and for 3 months with prednisolone, in decreasing doses. A bone marrow aspirate and core biopsy were performed. Hypoplastic bone marrow was observed. Once underlying infectious diseases and exposure to toxins were ruled out, a diagnosis of aplastic anaemia was made. The patient was treated with eltrombopag, a thrombopoietin receptor agonist that stimulates primitive haematopoietic stem cells, used for the treatment of aplastic anaemia in humans. One week after starting eltrombopag treatment, all the affected cellular lines were recovered. The patient continued in remission 7 months after treatment.
PB Wiley
YR 2023
FD 2023-07-25
LK https://hdl.handle.net/20.500.14352/104369
UL https://hdl.handle.net/20.500.14352/104369
LA eng
NO Rodriguez-Cobos A, Atencia S. Aplastic anaemia treated using eltrombopag in a dog. Vet Rec Case Rep. 2023; 11:e675. https://doi.org/10.1002/vrc2.675
NO 2023 Acuerdos transformativos CRUE
DS Docta Complutense
RD 5 abr 2025