RT Journal Article
T1 Pre-operative simulation of post-operative multifocal vision
A1 Maria Viñas, 
A1 Sara Aissati, 
A1 Mercedes Romero, 
A1 Clara Benedi-Garcia, 
A1 Nuria Garzon, 
A1 Francisco Poyales, 
A1 Carlos Dorronsoro, 
A1 Susana Marcos, 
A1 Garzón Jiménez, Nuria
AB While multifocal intraocular lenses (MIOLs) are increasingly implanted to correct for presbyopia, how one sees with a multifocal correction is hard to explain and imagine. The current study evaluates the quality of various visual simulating technologies by comparing vision with simulated MIOLs pre-operatively and the implanted MIOLs post-operatively in the same patients. Two simulation platforms were used: (1) a custom-developed adaptive optics (AO) system, with two visual simulator devices: a spatial light modulator (SLM) and an optotunable lens operating under temporal multiplexing (SimVis); and (2) a wearable, binocular, large field of view SimVis2Eyes clinical simulator (SimVis Gekko, 2Eyes Vision, Madrid, Spain). All devices were programmed to simulate a trifocal diffractive MIOL (POD F, FineVision, PhysIOL). Eight patients were measured pre-operatively simulating the trifocal lens and post-operatively with implantation of the same MIOL. Through-focus decimal visual acuity (TF VA) was measured (1) monocularly in monochromatic light using a four-alternative-forced-choice procedure in the AO system, and (2) binocularly using a clinical optotype in white light. Visual simulations pre-operatively predict well the TF VA performance found post-operatively in patients implanted with the real IOL. The average RMS difference between TF curves with the different visual simulators was 0.05 ± 0.01. The average RMS difference between the TF VA curves with the SimVis pre-operatively and the real MIOL post-operatively was 0.06 ± 0.01 in both platforms, and it was higher in cataract eyes (0.08 ± 0.01, on average across simulators) than in eyes with clear lens. In either group, the shape of the TF curves is similar across simulators and pre-and post-operatively. TF curves cross-correlated significantly between simulators (lag k = 0, rho = 0.889), as well as with results with the real MIOL implanted (lag k = 0, rho = 0.853). Visual simulations are useful programmable tools to predict visual performance with MIOLs, both in an AO environment and in a clinical simulator. Pre-operative visual simulations and post-operative data are in good agreement.
PB Optica Publishung group
SN 2156-7085
YR 2019
FD 2019-10-19
LK https://hdl.handle.net/20.500.14352/88860
UL https://hdl.handle.net/20.500.14352/88860
LA eng
NO Maria Vinas, Sara Aissati, Mercedes Romero, Clara Benedi-Garcia, Nuria Garzon, Francisco Poyales, Carlos Dorronsoro, and Susana Marcos, "Pre-operative simulation of post-operative multifocal vision," Biomed. Opt. Express 10, 5801-5817 (2019)
NO European Research Council
NO H2020 Marie Skłodowska-Curie Actions
NO Gobierno de España
NO PhysIOL Group (Bélgica)
DS Docta Complutense
RD 7 sept 2024