%0 Journal Article
%A Skolnick, Jeffrey
%A Kolinski, Andrzej
%A Brooks, Charles L.
%A Godzik, Adam
%A Rey Gayo, Antonio
%T A method for predicting protein structure from sequence
%D 1993
%@ 0960-9822
%U https://hdl.handle.net/20.500.14352/60167
%X The ability to predict the native conformation of a globular protein from its amino-acid sequence is an important unsolved problem of molecular biology. We have previously reported a method in which reduced representations of proteins are folded on a lattice by Monte Carlo simulation, using statistically-derived potentials. When applied to sequences designed to fold into four-helix bundles, this method generated predicted conformations closely resembling the real ones.
%~