RT Journal Article
T1 A method for predicting protein structure from sequence
A1 Skolnick, Jeffrey
A1 Kolinski, Andrzej
A1 Brooks, Charles L.
A1 Godzik, Adam
A1 Rey Gayo, Antonio
AB The ability to predict the native conformation of a globular protein from its amino-acid sequence is an important unsolved problem of molecular biology. We have previously reported a method in which reduced representations of proteins are folded on a lattice by Monte Carlo simulation, using statistically-derived potentials. When applied to sequences designed to fold into four-helix bundles, this method generated predicted conformations closely resembling the real ones.
PB Elsevier
SN 0960-9822
YR 1993
FD 1993
LK https://hdl.handle.net/20.500.14352/60167
UL https://hdl.handle.net/20.500.14352/60167
LA eng
DS Docta Complutense
RD 10 abr 2025