RT Journal Article T1 Surgical approach combining implantoplasty and reconstructivetherapy with locally delivered antibiotic in the treatment ofperi-implantitis: A prospective clinical case series A1 González Regueiro, Iria A1 Martínez Rodriguez, Natalia A1 Barona Dorado, Cristina A1 Sanz Sánchez, Ignacio A1 Montero Solís, Eduardo A1 Ata-Ali, Javier A1 Duarte, Fernando A1 Martínez González, José María AB Background: Nonsurgical treatment, resective surgery, reconstructive surgery, or combined approaches have been proposed for the treatment of peri-implantitis, with variable results.Purpose: To evaluate the 1-year clinical and radiographic outcomes following combined resective and reconstructive surgical treatment with topical piperacillin/tazobactam antibiotic in the management of peri-implantitis.Material and methods: Forty-three patients diagnosed with peri-implantitis were included. Surgical treatment consisted of implantoplasty of the supra-crestal component of the defect, the application of a topical antibiotic solution over the implant surface, and subsequent reconstruction of the intra-osseous component of the peri-implant defect. The primary outcome was disease resolution, defined as the absence of bleeding on probing (BoP) and/or suppuration on probing (SoP), a peri-implant pocket probing depth (PPD) ≤5 mm, and no bone loss >0.5 mm 1 year after surgery. Secondary outcomes included changes in BoP, PPD, SoP, and peri-implant marginal bone levels. One implant per patient was included in the analysis.Results: The treatment success rate of the 43 dental implants included in the study was 86% at 1 year after surgery. Mean PPD and BoP decreased from 6.41 ± 2.11 mm and 100% at baseline to 3.19 ± 0.99 mm (p < 0.001) and 14% (p < 0.001) at 1 year, respectively. SoP was significantly reduced from 48.8% at baseline to 0% 1 year after surgery (p < 0.001). Radiographically, a mean defect fill of 2.64 ± 1.59 mm was recorded (p < 0.001).Conclusions: The combination of a resective and reconstructive surgical approach together with locally delivered antibiotic achieved a high disease resolution rate after 1 year of follow-up and constitutes a viable option for the management of peri-implantitis. PB Wiley Periodicals SN 1523-0899 YR 2021 FD 2021-12-21 LK https://hdl.handle.net/20.500.14352/92210 UL https://hdl.handle.net/20.500.14352/92210 LA eng NO González Regueiro I, Martínez Rodriguez N, Barona Dorado C, et al. Surgical approach combining implantoplasty and reconstructive therapy with locally delivered antibiotic in the treatment of peri-implantitis: A prospective clinical case series. Clin Implant Dent Relat Res. 2021; 23(6): 864-873 DS Docta Complutense RD 18 ago 2024