RT Journal Article
T1 Probing the effect of the capping polyelectrolyte on the internal structure of Layer-by-Layer decorated nanoliposomes
A1 Mateos-Maroto, Ana
A1 Rubio, José
A1 Prévost, Sylvain
A1 Maestro, Armando
A1 González Rubio, Ramón
A1 Ortega Gómez, Francisco
A1 Guzmán Solís, Eduardo
AB HypothesisThe internal organization of polyelectrolyte layers deposited on colloidal templates plays a very important role for the potential applications of these systems as capsules for drug delivery purposes.ExperimentsThe mutual arrangement of oppositely charged polyelectrolyte layers upon their deposition on positively charged liposomes has been studied by combining up three different scattering techniques and Electronic Spin Resonance, which has provided information about the inter-layer interactions and their effect on the final structure of the capsules.FindingsThe sequential deposition of oppositely charged polyelectrolytes on the external leaflet of positively charged liposomes allows modulating the organization of the obtained supramolecular structures, impacting the packing and rigidity of the obtained capsules due to the change of the ionic cross-linking of the multi-layered film as a result of the specific charge of the last deposited layer. The possibility to modulate the properties of the LbL capsules by tuning the characteristics of the last deposited layers offers a very interesting route for the design of materials for encapsulation purposes with their properties controlled almost at will by changing the number of deposited layers and their chemistry.
PB Elsevier
SN 0021-9797
YR 2023
FD 2023
LK https://hdl.handle.net/20.500.14352/95163
UL https://hdl.handle.net/20.500.14352/95163
LA eng
NO Mateos-Maroto, Ana, et al. «Probing the Effect of the Capping Polyelectrolyte on the Internal Structure of Layer-by-Layer Decorated Nanoliposomes». Journal of Colloid and Interface Science, vol. 640, junio de 2023, pp. 220-29.  https://doi.org/10.1016/j.jcis.2023.02.086.
NO Ministerio de Ciencia, Innovación y Universidades (España)
NO European Commission
DS Docta Complutense
RD 6 oct 2024