RT Journal Article
T1 Valorisation of black mulberry and grape seeds: Chemical characterization and bioactive potential
T2 Valorización de las semillas de mora y uva: caracterización química y potencial bioactivo
A1 Gómez Mejía, Esther
A1 Lobo Roriz, Custódio
A1 Heleno, Sandrina
A1 Calhelha, Ricardo
A1 Dias, Maria Inês
A1 Pinela, José
A1 Rosales Conrado, Noelia
A1 León González, María Eugenia de
A1 Ferreira, Isabel
A1 Barros, Lillian
AB Grape (Vitis vinifera L. var. Albariño) and mulberry (Morus nigra L.) seeds pomace were characterized in terms of tocopherols, organic acids, phenolic compounds and bioactive properties. Higher contents of tocopherols (28 ± 1 mg/100 g fw) were obtained in mulberry, whilst grape seeds were richer in organic acids (79 ± 4 mg/100 g fw). The phenolic analysis of hydroethanolic extracts characterised grape seeds by catechin oligomers (36.0 ± 0.3 mg/g) and mulberry seeds by ellagic acid derivatives (3.14 ± 0.02 mg/g). Both exhibited high antimicrobial activity against multiresistant Staphylococcus aureus MIC = 5 mg/mL) and no cytotoxicity against carcinogenic and non-tumour primary liver (PLP) cells. Mulberry seeds revealed the strongest inhibition (p < 0.05) against thiobarbituric reactive substances (IC50 = 23 ± 2 µg/mL) and oxidative haemolysis (IC50 at 60 min = 46.0 ± 0.8 µg/mL). Both seed by-products could be exploited for the developing of antioxidant-rich ingredients with health benefits for industrial application.
PB Elsevier Sci Ltd
SN 0308-8146
YR 2021
FD 2021
LK https://hdl.handle.net/20.500.14352/91805
UL https://hdl.handle.net/20.500.14352/91805
LA eng
NO Esther Gómez-Mejía, Custódio Lobo Roriz, Sandrina A. Heleno, Ricardo Calhelha, Maria Inês Dias, José Pinela, Noelia Rosales-Conrado, María Eugenia León-González, Isabel C.F.R. Ferreira, Lillian Barros, Valorisation of black mulberry and grape seeds: Chemical characterization and bioactive potential, Food Chemistry, Volume 337, 2021, 127998, ISSN 0308-8146, https://doi.org/10.1016/j.foodchem.2020.127998
NO Foundation for Science and Technology (Portugal)
NO Universidad Complutense de Madrid
NO European Commission
DS Docta Complutense
RD 6 abr 2025