RT Journal Article
T1 Water-soluble hollow nanocrystals from self-assembly of AIEE-active Pt(II) metallomesogens
A1 Cuerva de Alaiz, Cristian
A1 Fernández-Lodeiro, Javier
A1 Cano Esquivel, María Mercedes
A1 Capelo-Martínez, José Luis
A1 Lodeiro, Carlos
AB Luminescent hollow micro- and nanocrystals have been successfully obtained taking advantage of the self-assembly behavior and the aggregation-induced emission enhancement properties of several bispyrazolate Pt(II) metallomesogens decorated with four terminal alkyl chains. Oil-in-water droplets have been used to confine the Pt(II) compounds and drive them to be self-assembled via intermolecular Pt···Pt interactions into spherical aggregates of about 200 or 50 nm. Evaporation of the oil phase generates highly-stable aqueous dispersions of nanocrystals that emit a bright orange light as a result of the existence of 3MMLCT excited states. Different methods and conditions have been tested for studying the effect of several parameters such as the temperature and the stirring speed in the final particle size and in the polydispersity index. Moreover, the micro- and nanocrystals are able to entrap hydrophobic drugs between the alkyl chains of the compounds, forming stable dispersions of drug-loaded capsules in water. The droplet method is applied in the area of metallomesogens for the first time to synthesize self-assembled Pt(II) nanocapsules, which opens a new field of study that could allow the use of these liquid crystal materials in biomedical applications.
PB Springer Nature
SN 1998-0124
YR 2021
FD 2021
LK https://hdl.handle.net/20.500.14352/93986
UL https://hdl.handle.net/20.500.14352/93986
LA eng
NO Cuerva C, Fernández-Lodeiro J, Cano M, Capelo-Martínez JL, Lodeiro C. Water-soluble hollow nanocrystals from self-assembly of AIEE-active Pt(II) metallomesogens. Nano Res. 2021, 14, 245–254
NO Associate Laboratory for Green Chemistry (Portugal)
NO PROTEOMASS Scientific Society (Portugal)
NO Fundación Alfonso Martín Escudero (España)
DS Docta Complutense
RD 14 dic 2025