TY - JOUR AU - Bepirszcz, Kamila AU - Mazzetta, Anna Maria AU - Gómez-Carpintero Jiménez, Jorge AU - Sánchez Cebrián, Juan Domingo AU - González Matilla, Juan Francisco AU - Menéndez Ramos, José Carlos PY - 2025 DO - 10.1021/acssuschemeng.4c09608 SN - 2168-0485 SN - 2168-0485 UR - https://hdl.handle.net/20.500.14352/134634 T2 - ACS Sustainable Chemistry & Engineering AB - Tetrazole derivatives are very important compounds in medicinal chemistry, and their preparation typically requires multistep sequences. Therefore, the regioselective N-alkylation of tetrazoles is a highly significant synthetic objective. We have... LA - eng M2 - 7332 PB - ACS Publications KW - tetrazole KW - regioselectivity KW - solid-state chemistry KW - ball milling KW - primary carbamates TI - Regioselective N-2 Alkylation of Tetrazoles with Phenacyl Halides under Mechanochemical Conditions and Its Application to a Solid-State Synthesis of the Antiepileptic Drug Cenobamate TY - journal article VL - 13 ER -