%0 Journal Article
%A Cabezas Quintario, María Antonia
%A Zenzola, Víctor
%A Arguelles, Miguel
%A Pérez Fernández, Elia
%T Androgen receptor as prognostic marker in triple-negative breast cancer patients
%D 2018
%@ 2472-4971
%U https://hdl.handle.net/20.500.14352/116473
%X Purpose: The purpose of this study was to assess the prognostic impact of androgen receptor (AR) expression inpatients with triple-negative breast cancer (TNBC).Methods/patients: 101 patients treated for primary TNBC without distant metastasis from 1999 to 2015 wereidentified from breast surgery database. Kaplan-Meier and Cox regression models evaluated disease-free survival(DFS) and overall survival (OS).Results: AR expression was positive (IHC>1%) in 40% of patients. OS at 36 and 60 months was 86% and 80%in AR-negative patients, and 100% and 96% in AR-positive patients (log rank test 0.036). DFS at 36 and 60 monthswas 78% and 68% in AR-negative and 92% and 89% in AR-positive (log rank test 0.075).Conclusions: Patients without AR expression have a significant correlation with poor outcome
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