RT Journal Article
T1 Large cell neuroendocrine carcinoma on the floor of the mouth: a rare entity in an unusual location
A1 Agea Martínez, M.
A1 Navarro Cuéllar, Ignacio
A1 Sada Urmeneta, A.
A1 Alijo Serrano, F.
A1 Navarro Cuéllar, Carlos
AB Neuroendocrine carcinomas (NEC) are a group of malignant neoplasms usually located in the lungs or gastrointestinal tract. Fewer cases are located in the head and neck, and in these rare presentations, the lingual tonsil, larynx, and major salivary glands are the most frequently affected sites. NECs exhibit similar characteristics regardless of where they arise. However, because these neoplasms are rare, a clear understanding of their aetiopathogenesis has yet to be described, and options for treatment have varied and are not unified. A rare NEC of the floor of the mouth is reported here; it appears that this location has not been reported previously. The diagnosis was established through histopathological analysis, and the patient underwent systemic treatment. He had a partial response to treatment in the first 3 months, but died 6 months after the initial diagnosis. This highly uncommon tumour can pose a significant diagnostic challenge for clinicians and pathologists alike and can result in diagnostic delay.
PB Elsevier
SN 0901-5027
YR 2021
FD 2021-09-02
LK https://hdl.handle.net/20.500.14352/108676
UL https://hdl.handle.net/20.500.14352/108676
LA eng
NO Agea Martínez M, Navarro Cuéllar I, Sada Urmeneta A, Alijo Serrano F, Navarro Cuéllar C. Large cell neuroendocrine carcinoma on the floor of the mouth: a rare entity in an unusual location. Int J Oral Maxillofac Surg. 2022 Jun;51(6):742-745. doi: 10.1016/j.ijom.2021.08.021. Epub 2021 Sep 2. PMID: 34481737.
DS Docta Complutense
RD 18 abr 2025