TY - JOUR AU - Roscales GarcĂ­a, Silvia AU - Bechmann, Nicole AU - Pietzsch, Jens AU - Kniess, Torsten PY - 2019 DO - 10.3987/COM-19-14048 UR - https://hdl.handle.net/20.500.14352/126401 T2 - Heterocycles AB - A series of 5-methyl-3,4-diaryl-substituted 1H-pyrazoles, N-isosteres of valdecoxib, was synthesized by a [3+2] cycloaddition/[1,5] sigmatropic rearrangement sequence starting from tosylhydrazine, aryl methyl ketones and terminal aryl alkynes bearing... LA - eng M2 - 416 TI - One-pot cascade synthesis of pyrazole based isosteres of valdecoxib by A [3+2] cycloaddition sequence and evaluation of their cox inhibitory activity TY - journal article VL - 98 ER -