TY  - JOUR
AU  - Martín Morales, Lorena
AU  - Manzano Figueroa, Sara
AU  - Rodrigo Faus, María
AU  - Vicente Barrueco, Adrian
AU  - Lorca, Víctor
AU  - Núñez Moreno, Gonzalo
AU  - Bragado Domingo, Paloma
AU  - Porras Gallo, María Almudena
AU  - Caldes, Trinidad
AU  - Garre, Pilar
AU  - Gutiérrez Uzquiza, Álvaro
PY  - 2022
DO  - 10.1002/ijc.34289
SN  - 0020-7136
UR  - https://hdl.handle.net/20.500.14352/72600
T2  - International Journal of Cancer
AB  - Abstract Matrix metalloproteinase-11 (MMP11) is an enzyme with proteolytic activity against matrix and nonmatrix proteins. Although most MMPs are secreted as inactive proenzymes and are later activated extracellularly, MMP11 is activated...
LA  - eng
PB  - Wiley
KW  - Colorectal cancer
KW  - Familial colorectal cancer type X
KW  - Matrix metalloproteinase 11
KW  - Proline for serine exchange in the 78 amino acid position of a protein
KW  - Whole exome sequencing
TI  - Germline gain‐of‐function MMP11 variant results in an aggressive form of colorectal cancer
TY  - journal article
ER  -