TY - JOUR AU - Chioua, Mourad AU - Pérez Peña, Javier AU - García Font, Nuria AU - Moraleda, Ignacio AU - Iriepa, Isabel AU - Soriano, Elena AU - Marco Contelles, José AU - Oset Gasque, María Jesús PY - 2015 DO - 10.4155/FMC.15.35 SN - 1756-8919 UR - https://hdl.handle.net/20.500.14352/34805 T2 - Future medicinal chemistry AB - Aim: Due to the complex nature of Alzheimer’s disease, there is a renewed search for multipotent, nonhepatotoxic tacrines. Results: This paper describes the synthesis and in vitro biological evaluation of eight new racemic... LA - eng M2 - 845 PB - Future Science KW - Tacrine KW - Butyrylcholinesterase KW - ADMET KW - Molecular modeling TI - Pyranopyrazolotacrines as nonneurotoxic, Aβ-anti-aggregating and neuroprotective agents for Alzheimer’s disease TY - journal article VL - 7 ER -