RT Journal Article
T1 An overview of the use of nanoparticles in vaccine development
A1 Lozano Borregón, Daniel
A1 Larraga, Vicente
A1 Vallet Regí, María Dulce Nombre
A1 Manzano García, Miguel
AB Vaccines represent one of the most significant advancements in public health since they prevented morbidity and mortality in millions of people every year. Conventionally, vaccine technology focused on either live attenuated or inactivated vaccines. However, the application of nanotechnology to vaccine development revolutionized the field. Nanoparticles emerged in both academia and the pharmaceutical industry as promising vectors to develop future vaccines. Regardless of the striking development of nanoparticles vaccines research and the variety of conceptually and structurally different formulations proposed, only a few of them advanced to clinical investigation and usage in the clinic so far. This review covered some of the most important developments of nanotechnology applied to vaccine technologies in the last few years, focusing on the successful race for the preparation of lipid nanoparticles employed in the successful anti-SARS-CoV-2 vaccines.
PB MDPI
YR 2023
FD 2023-06-09
LK https://hdl.handle.net/20.500.14352/104075
UL https://hdl.handle.net/20.500.14352/104075
LA eng
NO Lozano, D.; Larraga, V.; Vallet-Regí, M.; Manzano, M. An Overview of the Use of Nanoparticles in Vaccine Development. Nanomaterials 2023, 13, 1828. https://doi.org/10.3390/nano13121828
NO 2023 Descuentos MDPI
NO European Research Council
NO Fondo Europeo de Desarrollo Regional (FEDER)
NO Ministerio de Ciencia e Innovación (España)
NO CM-React Anticipa-UCM
DS Docta Complutense
RD 10 abr 2025