RT Journal Article
T1 Spanish adaptation and validation of the ALS Depression Inventory-12 (ADI-12) in patients with Amyotrophic Lateral Sclerosis
A1 Sancho Cantus, David
A1 Cubero Plazas, Laura
A1 Privado Zamorano, Jesús
A1 Aguilar García-Iturrospe, Eduardo Jesús
A1 Cañabate Ros, Montserrat
A1 Navarro Illana, Esther
A1 de la Rubia Ortí, José Enrique
AB Background. Patients with Amyotrophic Lateral Sclerosis (ALS) have a higher preva- lence of mood disorders, including depression, than the general population. Non-specific measurement instruments have been used to evaluate depression in these patients, which complicates accurate diagnosis. The ALS Depression Inventory (ADI-12) exclusively as- sesses depressive symptoms in patients with ALS. Aim. To adapt and validate the ADI-12 in a Spanish sample. Methods. A selective design was used with 74 patients with ALS, using the ADI-12 questionnaire. The original instrument was translated and back-translated into Spanish. The internal structure, temporal stability, convergent, and discriminant validity of the instrument were analyzed. Results. Two confirmatory models showed internal validity (p = 0.502 for the one-factor model, p = 0.507 for the two-factor model). The Cronbach’s alpha (0.900 in the first measurement and 0.889 in the second one) indicated a high internal consistency of the test. The Pearson correlation (0.90) indicated high temporal stability. In terms of convergent validity, the ADI-12 showed moderate correlations with the Beck Anxiety Inventory (BAI) (0.51–0.58), and low correlations with time since ALS diagnosis (–0.26 to –0.27). Limitations. The main limitation of the present study was the small sample size. Conclusions. The ADI-12 is fitted to a single general factor of depression, and the scale shows high internal consistency and high temporal stability, therefore, its use is recommended for the diagnosis of depression in patients with ALS.
PB Elsevier
YR 2024
FD 2024-01
LK https://hdl.handle.net/20.500.14352/129392
UL https://hdl.handle.net/20.500.14352/129392
LA eng
NO Sancho-Cantus, D., Cubero-Plazas, L., Privado, J., García-Iturrospe, E. J. A., Cañabate Ros, M., Navarro-Illana, E., & de la Rubia Ortí, J. E. (2024). Spanish adaptation and validation of the als depression inventory-12 (ADI-12) in patients with amyotrophic lateral sclerosis. Archives of Medical Research, 55(1), 102936. https://doi.org/10.1016/j.arcmed.2023.102936
NO Universidad Católica de Valencia
DS Docta Complutense
RD 26 feb 2026